DNA Modification

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August 31, 2022

DNA Glycosylase: Overview In the cellular environment, DNA is under a constant threat of getting involved in a chemical reaction. It can be either due to alkylation, oxidation, or deamination. These r...

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DNase: Definition & Overview of Deoxyribonuclease

April 28, 2022

DNA Modification

DNase: Definition & Overview of Deoxyribonuclease

What Is DNase? Deoxyribonuclease (DNase) is a class of nuclease enzymes that cleaves the DNA molecule. It breaks the phosphodiester bond formed between two nucleotides of dsDNA or ssDNA, by cleaving e...

A strand of DNA with two bandaids placed over different places.

T4 Polynucleotide Kinase: Definition & Overview

April 4, 2022

DNA Modification

T4 Polynucleotide Kinase: Definition & Overview

Definition of T4 Polynucleotide Kinase Nucleic acids can be modified at the polynucleotide level through many enzymatic reactions. It includes methylation of both DNA and RNA, glycosylation of DNA, an...

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Overview of Recombinase: Definition & Functions

March 21, 2022

DNA Modification

Overview of Recombinase: Definition & Functions

Definition of Recombinase Recombinase is a family of enzymes that catalyze site-specific recombination events within DNA. Site-specific DNA recombination is a process in which DNA strands are br...

A magnifying glass with an eye inside the lens following around a target as it inspects different strands of DNA.

Exonuclease: Overview & Definition of this Important Enzyme

March 3, 2022

DNA Modification

Exonuclease: Overview & Definition of this Important Enzyme

Exonuclease Definition In biochemistry, nucleases are a diverse class of hydrolytic enzymes that carry out hydrolysis of phosphodiester bonds of nucleic acids — DNA and RNA. Nucleases attack the hydro...

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An Overview of Protein Kinases: Definition & Functions

March 3, 2022

DNA Modification

An Overview of Protein Kinases: Definition & Functions

Regulation and Function of Protein Kinase There are about 500 protein kinase encoding genes in the human genome which represents 2% of all the human genes. Kinase is the name given to an enzyme that a...