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Exonuclease Definition In biochemistry, nucleases are a diverse class of hydrolytic enzymes that carry out hydrolysis of phosphodiester bonds of nucleic acids — DNA and RNA. Nucleases attack the hydro...
March 2022
Regulation and Function of Protein Kinase There are about 500 protein kinase encoding genes in the human genome which represents 2% of all the human genes. Kinase is the name given to an enzyme that a...
March 2022
What Are Endonucleases? Various enzymes are involved in tampering with DNA by breaking and forming the bonds between nucleotides. One is a nuclease, a class of enzyme that hydrolyzes the polynucleotid...
February 2022
Methyltransferase Definition Methyltransferases are a group of enzymes that add a methyl group to their substrates. Over 95% of this group of enzymes use S-adenosylmethionine (SAM) as their methyl don...
February 2022
What is the Joint Commission International (JCI)? The Joint Commission International (JCI) is a non-profit, U.S-based, international accreditation organization that certifies healthcare companie...
February 2022
What is dTTP? 2′-deoxythymidine 5′-triphosphate (or dTTP) is one of the nucleotide bases among three other dNTPs (deoxynucleoside triphosphate)—dATP, dGTP, and dCTP—that are involved in th...
February 2022
Conformity Assessment: Requirements for Certification Bodies Certifying Products, Processes, & Services ISO (International Organization for Standardization) and IEC (International Electrotechnical...
February 2022
What is Deoxycytidine Triphosphate (dCTP)? 2′-deoxycytidine 5′-triphosphate (or dCTP) is a nucleoside triphosphate (a nucleotide), containing cytosine as its pyrimidine base. It also...
February 2022
Polymerase Chain Reaction (PCR) Basics Did you know Mullis and Michael Smith won the Nobel Prize for discovering the Polymerase Chain Reaction (PCR) in 1983? This groundbreaking technology-enabled sci...
February 2022
What is a Real-time PCR Master Mix? PCR master mix, as the name suggests, is a premixed solution of all reagents and essential components required to run a PCR assay. It contains dNTPs (dATP, dGTP, dT...
February 2022
What is dGTP? Deoxyguanosine triphosphate (dGTP) is a nucleotide with a purine base (guanine), deoxyribose sugar, and three phosphate groups. It’s one of the four dNTPs (deoxynucleoside triphosphate) ...
February 2022
What’s the Relation Between CAP & CLIA? When labs are in compliance with CLIA (Clinical Laboratory Improvement Amendments), it is validated with a CLIA certificate. After becoming CLIA-certified, ...
February 2022
