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In-depth articles covering the various methods and applications used in the life sciences to further scientific study and innovation.
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Definition of T4 Polynucleotide Kinase Nucleic acids can be modified at the polynucleotide level through many enzymatic reactions. It includes methylation of both DNA and RNA, glycosylation of DNA, an...
April 2022
Protein gel electrophoresis, or simply protein electrophoresis, is a common technique used in laboratories to separate biomolecules, including DNA, RNA, and proteins, based on size or molecular weight...
April 2022
A huge part of being an entrepreneur in the life sciences is fundraising. The amount of money (and time) it can take to fund research and development and bring a product to market, whether it’s someth...
March 2022
How Do Business Entities Differ From One Another? Are you a new business owner or aspiring entrepreneur trying to figure out the differences between business entities? The similarities and differences...
March 2022
Advantages & Disadvantages of Incorporating in Delaware Are you a biotechnology or life sciences startup co-founder? Have you recently incorporated your early-stage startup? Like entrepreneurs in ...
March 2022
Definition of Recombinase Recombinase is a family of enzymes that catalyze site-specific recombination events within DNA. Site-specific DNA recombination is a process in which DNA strands are br...
March 2022
Regulation and Function of Protein Kinase There are about 500 protein kinase encoding genes in the human genome which represents 2% of all the human genes. Kinase is the name given to an enzyme that a...
March 2022
Exonuclease Definition In biochemistry, nucleases are a diverse class of hydrolytic enzymes that carry out hydrolysis of phosphodiester bonds of nucleic acids — DNA and RNA. Nucleases attack the hydro...
March 2022
Methyltransferase Definition Methyltransferases are a group of enzymes that add a methyl group to their substrates. Over 95% of this group of enzymes use S-adenosylmethionine (SAM) as their methyl don...
February 2022
What Are Endonucleases? Various enzymes are involved in tampering with DNA by breaking and forming the bonds between nucleotides. One is a nuclease, a class of enzyme that hydrolyzes the polynucleotid...
February 2022